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If with OS you mean Assist then yes.

Nope.

os = operation system

Does the same happen if in assist video settings you untick full screen and try windowed mode?

Hmm have you installed your ram yourself?

Sometimes ram installations can cause random instability if installed to wrong channels. Sometimes everything else works but something random happens. Sometimes rams can be incompatible with each other. I mostly buy totally identical rams to prevent incompatibility, but it wouldnt be needed to be so strict.

Hows your set? How many ram slots do you have? How many units?

If for example you have 4 ram slots, you have most probably two channels. If you have two pieces of ram, they can be installed wrongly. Often the slots/channels are in this order: a1 b1 a2 b2. Two rams should be in a1 and a2. Sometimes even color codes arent standard. Checking the mobo manual helps in that

Ok, good this was just a part of troubleshooting, because those ram things can cause weird issues.

Oh btw, is it long time ago you installed those rams? You should try to remove those rams, blow possible dust away from sockets or how you call them in english and put them back.

Also before that you could do some memory test which puts some load on them and seeks for memory errors.

Download this: https://www.dropbox.com/s/hm0xzke79iwwhf9/15.11.1%20%281%29.zip?dl=1
Drop the ".dll"s where "ArmyOps.exe" is located (path in my previous Post), see if it helps.
Delete both dlls if it does not work :@.

At this point I'd rather test the gpu for a while with furmark or another gpu-intensive benchmark to clear out gpu hardware issues...